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锚蛋白重复结构域蛋白22抗体
  • 产品货号:
    BN41404R
  • 中文名称:
    锚蛋白重复结构域蛋白22抗体
  • 英文名称:
    Rabbit anti-ANKRD22 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41404R-100ul

    100ul

    ¥2120.00

    交叉反应(总):Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,;推荐应用:WB,

  • BN41404R-200ul

    200ul

    ¥3140.00

    交叉反应(总):Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,;推荐应用:WB,

产品描述

英文名称ANKRD22
中文名称锚蛋白重复结构域蛋白22抗体
别    名Ankrd22; Ankyrin repeat domain 22; Ankyrin repeat domain-containing protein 22; ANR22_HUMAN.  
研究领域细胞生物  免疫学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞核 细胞浆 细胞膜 细胞外基质 分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ANKRD22:51-150/191 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Similarity:
Contains 4 ANK repeats.

SWISS:
Q5VYY1

Gene ID:
118932

Database links:

Entrez Gene: 118932 Human

Entrez Gene: 52024 Mouse

SwissProt: Q5VYY1 Human

SwissProt: Q9D3J5 Mouse

Unigene: 217484 Human

Unigene: 183030 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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