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溶质载体蛋白家族47成员A1抗体
  • 产品货号:
    BN41376R
  • 中文名称:
    溶质载体蛋白家族47成员A1抗体
  • 英文名称:
    Rabbit anti-SLC47A1 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

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  • BN41376R-100ul

    100ul

    ¥2120.00

    交叉反应(总):Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep,;推荐应用:WB,

  • BN41376R-200ul

    200ul

    ¥3140.00

    交叉反应(总):Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep,;推荐应用:WB,

产品描述

英文名称SLC47A1
中文名称溶质载体蛋白家族47成员A1抗体
别    名1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.  
研究领域肿瘤  细胞生物  信号转导  细胞膜蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量58kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SLC47A1:211-310/530 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

Function:
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Subcellular Location:
Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

Tissue Specificity:
Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

Similarity:
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

SWISS:
Q96FL8

Gene ID:
55244

Database links:

Entrez Gene: 55244 Human

Omim: 609832 Human

SwissProt: Q96FL8 Human

Unigene: 232054 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.