核通道蛋白SEH1L抗体

产品货号：

BN41350R
中文名称：

核通道蛋白SEH1L抗体
英文名称：

Rabbit anti-SEH1L Polyclonal antibody
品牌：

Biorigin

货号

产品规格

售价

备注
BN41350R-100ul

100ul

¥2120.00

交叉反应（总）:Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,;推荐应用:IHC-P,
BN41350R-200ul

200ul

¥3140.00

交叉反应（总）:Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,;推荐应用:IHC-P,

产品描述

英文名称	SEH1L
中文名称	核通道蛋白SEH1L抗体
别名	Nucleoporin SEH1; Nup107-160 subcomplex subunit SEH1; SEC13-like protein; SEC13L; Seh 1; SEH1-like (S. cerevisiae); SEH1_HUMAN; SEH1A; SEH1B; SEH1L
研究领域	细胞生物免疫学染色质和核信号信号转导表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, )
产品应用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	40kDa
细胞定位	细胞核
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human SEH1L:1-100/360
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	Seh1 is a 421 amino acid protein belonging to the WD repeat Sec13 family. Localized to the nucleus, Seh1 is a component of the nuclear pore complex Nup107-160. Nuclear pore complexes control bidirectional transport of macromolecules between the cytoplasm and the nucleus. All components of the complex Nup107-160, including Seh1, localize to the kinetochores during mitosis. Seh1 is expressed as two isoforms produced by alternative splicing and contains six WD repeats. Function: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Subcellular Location: Chromosome; centromere; kinetochore. Nucleus; nuclear pore complex. Similarity: Belongs to the WD repeat SEC13 family. Contains 6 WD repeats. SWISS: Q96EE3 Gene ID: 81929 Database links: Entrez Gene: 81929 Human Omim: 609263 Human SwissProt: Q96EE3 Human Unigene: 301048 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.