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锌指蛋白Zdhhc18抗体
  • 产品货号:
    BN41342R
  • 中文名称:
    锌指蛋白Zdhhc18抗体
  • 英文名称:
    Rabbit anti-ZDHHC-18 Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN41342R-100ul

    100ul

    ¥2120.00

    交叉反应(总):Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,;推荐应用:WB,

  • BN41342R-200ul

    200ul

    ¥3140.00

    交叉反应(总):Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,;推荐应用:WB,

产品描述

英文名称ZDHHC-18
中文名称锌指蛋白Zdhhc18抗体
别    名DHHC-18; DKFZp667O2416; Palmitoyltransferase ZDHHC18; ZDH18_HUMAN; Zdhhc18; Zinc finger DHHC domain-containing protein 18.  
研究领域细胞生物  免疫学  信号转导  转录调节因子  锌指蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ZDHHC-18:265-360/388 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC1 (zinc finger, DHHC-type containing 1), also known as ZNF377 (zinc finger protein 377) or C16orf1, is a 485 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. Expressed in fetal heart, lung and kidney and also present in adult lung and pancreas, ZDHHC1 functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Like ZDHHC1, ZDHHC5, ZDHHC6, ZDHHC7 and ZDHHC18 each contain one DHHC-type zinc finger through which they convey palmitoyltransferase activity against a broad range of substrates, including H-Ras, SNAP 25 and GABAA R proteins.

Function:
Has palmitoyltransferase activity towards HRAS and LCK.

Subcellular Location:
Membrane; Multi-pass membrane protein

Similarity:
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
Contains 1 DHHC-type zinc finger.

SWISS:
Q9NUE0

Gene ID:
84243

Database links:

Entrez Gene: 84243 Human

Entrez Gene: 503610 Mouse

Entrez Gene: 362613 Rat

SwissProt: Q9NUE0 Human

SwissProt: Q5Y5T2 Mouse

SwissProt: Q2TGJ1 Rat

Unigene: 523710 Human

Unigene: 331948 Mouse

Unigene: 203345 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.