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首页>>免疫学>>一抗>>HOXB4抗体
HOXB4抗体
  • 产品货号：
    BN40942R
  • 中文名称：
    HOXB4抗体
  • 英文名称：
    Rabbit anti-HOXB4 Polyclonal antibody
  • 品牌：
    Biorigin

  • 货号

    产品规格

    售价

    备注

  • BN40942R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

  • BN40942R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Sheep) 推荐应用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

产品描述

英文名称HOXB4
中文名称HOXB4抗体
别    名Homeo box 2F; Homeo box B4; Homeobox 2F; Homeobox B4; Homeobox protein Hox B4; Homeobox protein HoxB4; HOX 2; Hox 2.6; Hox 2F; HOX B4; HOX2; HOX-2 Hox2.6; Hox2F; HOXB 4; HOXB-4.  
研究领域肿瘤  免疫学  信号转导  干细胞  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量28kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HOXB4:151-251/251 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍HOXB4 is a homeodomain-containing transcription factor with diverse roles in embryonic development and the regulation of adult stem cells. It promotes proliferation of hematopoietic stem cells and can both activate and repress apoptosis.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Antp homeobox family. Deformed subfamily.
Contains 1 homeobox DNA-binding domain.

SWISS:
P17483

Gene ID:
3214

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OXB4通过激活不同的信号通路增强HSC的自我更新,同时又不影响维持正常稳态造血的调控机制。提高HOXB4的表达水平,能够极大地增强HSC的自我更新功能,但基本不影响细胞的分化、系特异性及终末细胞的形态和功能。另外，HOXB4还可增强胚胎干细胞(embryonic stem cell,ESC)的造血潜能,促进ESC向造血细胞分化。