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嗜酸粒细胞趋化蛋白3抗体
  • 产品货号:
    BN40252R
  • 中文名称:
    嗜酸粒细胞趋化蛋白3抗体
  • 英文名称:
    Rabbit anti-CCL26 Signal peptide Polyclonal antibody
  • 品牌:
    Biorigin
  • 货号

    产品规格

    售价

    备注

  • BN40252R-100ul

    100ul

    ¥2120.00

    交叉反应(总):Human,Mouse,Rat,;推荐应用:IHC-P,

  • BN40252R-200ul

    200ul

    ¥3140.00

    交叉反应(总):Human,Mouse,Rat,;推荐应用:IHC-P,

产品描述

英文名称CCL26 Signal peptide
中文名称嗜酸粒细胞趋化蛋白3抗体
别    名C-C motif chemokine 26; CC chemokine IMAC; CCL 26; CCL26; Chemokine (C C motif) ligand 26; Eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MIP 4a; MIP 4alpha; MIP-4-alpha; MIP4a; MIP4alpha; SCYA 26; SCYA26; Small inducible cytokine A26; Small inducible cytokine subfamily A (Cys Cys) member 26; Small inducible cytokine subfamily A member 26; Small-inducible cytokine A26; Thymic stroma chemokine 1; Thymic stroma chemokine-1; TSC 1; TSC-1; TSC1; CCL26 Signal peptide; .  
研究领域细胞生物  免疫学  细胞凋亡  趋化因子  泛素  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Rat,  (predicted: Mouse, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量11kDa
细胞定位分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from rat CCL26 Signal peptide:1-70/94 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]

Function:
Chemotactic for eosinophils and basophils. Binds to CCR3.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Tissue Specificity:
Ubiquitously expressed at low levels in various tissues including heart and ovary.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

SWISS:
N/A

Gene ID:
292673

Database links:

Entrez Gene: 10344 Human

Entrez Gene: 541307 Mouse

Omim: 604697 Human

SwissProt: Q9Y258 Human

Unigene: 131342 Human

Unigene: 376459 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.